Inspra 50mg Tablets 28`s

Inspra, also known as Eplerenone, serves as an aldosterone antagonist and potassium-sparing diuretic, primarily prescribed to manage chronic heart failure and hypertension, especially in individuals with resistant hypertension caused by elevated aldosterone levels. This medication, a steroidal antimineralocorticoid belonging to the spironolactone group, acts as a selective aldosterone receptor antagonist (SARA). Eplerenone demonstrates higher selectivity towards the mineralocorticoid receptor compared to spironolactone, with minimal binding to androgen, progestogen, glucocorticoid, or estrogen receptors.

In the medical realm, Eplerenone, under the brand name Inspra, exhibits significant efficacy in various conditions:

1. Heart failure: Eplerenone mitigates mortality risk, particularly in patients recovering from recent myocardial infarction or heart attack.
2. Hypertension: Eplerenone effectively reduces blood pressure levels among individuals with primary hypertension. Furthermore, it diminishes arterial stiffness and vascular endothelial dysfunction.