Dapsone 100 mg 100’s


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Product Description

Dapsone 100 mg 100’s contain Dapsone which belongs to a group of medicine called antibacterials. It is used to treat leprosy and skin problems. In combination with pyrimethamine it helps to prevent malaria. It also prevents pneumonia in immunodeficient patients, especially in AIDS patients.

Each tablet contains 100mg Dapsone PhEur.

?Therapeutic indications

1) As part of a multi-drug regimen in the treatment of all forms of leprosy.

2) Treatment of dermatitis herpetiformis and other dermatoses.

3) Prophylaxis of malaria in combination with pyrimethamine.

4) Prophylaxis of Pneumocystis carinii pneumonia in immunodeficient subjects, especially AIDS patients.


4.2 Posology and method of administration


Adults and children over 12 years:

Multibacillary leprosy (3-drug regimen):?100mg daily for at least two years.

Paucibacillary leprosy (2-drug regimen):?100mg daily for at least six months.

Malaria prophylaxis:?100mg weekly with 12.5mg pyrimethamine.

Dermatitis herpetiformis:?Initially 50mg daily, gradually increased to 300mg daily if required. Once lesions have begun to subside, the dose should be reduced to a minimum as soon as possible, usually 25-50mg daily, which may be continued for a number of years. Maintenance dosage can often be reduced in patients receiving a gluten-free diet.

Pneumocystis carinii pneumonia:?In combination with trimethoprim, 50-100mg daily; 100mg twice weekly or 200mg once weekly.


Children 6-12 years:

Multibacillary leprosy (3-drug regimen):?50mg daily for at least two years.

Paucibacillary leprosy (2-drug regimen):?50mg daily for at least six months.

Elderly:?Dosage should be reduced in the elderly where there is an impairment of hepatic function.


Method of Administration

For oral administration.