Levemir FlexPen is indicated to improve glycemic control in adult and pediatric patients with diabetes mellitus.
Levemir? is not recommended for the treatment of diabetic ketoacidosis.
Levemir??is contraindicated during episodes of hypoglycemia and in patients hypersensitive to Levemir??or any of its excipients. Reactions have included anaphylaxis.
Never Share a Levemir??FlexTouch? Pen, Needle, or Syringe Between Patients
Hyperglycemia or Hypoglycemia with Changes in Insulin Regimen: Changes in an insulin regimen may affect glycemic control and predispose to hypoglycemia or hyperglycemia.
Hypoglycemia:?Hypoglycemia is the most common adverse reaction of insulin, including Levemir?, and may be life-threatening.
Hypersensitivity and Allergic Reactions:?If hypersensitivity reactions occur, discontinue Levemir?; treat per standard of care and monitor until symptoms and signs resolve. Levemir??is contraindicated in patients who have had hypersensitivity reactions to insulin detemir or any of the excipients.
Hypokalemia:?All insulin products, including Levemir?, cause a shift in potassium from the extracellular to intracellular space, possibly leading to hypokalemia.
Fluid Retention and Heart Failure with Concomitant Use of PPAR-gamma Agonists: Thiazolidinediones (TZDs), which are peroxisome proliferator-activated receptor (PPAR)-gamma agonists, can cause dose-related fluid retention, particularly when used in combination with insulin